Found 225 matching trials
Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04) PHASE3 This study will evaluate the efficacy and safety of trastuzumab deruxtecan ...
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Instituto Medico Especializado Alexander Fleming
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A Randomized Secondary Adjuvant Treatment Intervention Study Comparing Trastuzumab-Deruxtecan to SOC Therapy in eBC Patients With Molecular Relapse PHASE3 Prospective, multi-center, randomized, open label comparative Phase III stu...
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University Clinic Ulm
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A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors PHASE2 This is an open-label, multicenter, Phase II study to evaluate the efficacy...
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Active Not Recruiting
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Megestrol Acetate for Fatigue Management in T-DXd Treated Breast Cancer PHASE3 This study aims to evaluate whether the combination of Megestrol Acetate at...
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Sun yat-Sen University Cancer Center
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T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis PHASE2 A phase II, open-label, multicenter, randomized controlled trial exploring ...
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Fudan University Shanghai Cancer Center
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Scalp Cooling in MBC PHASE2 This research is being done to compare rates of hair loss of people with me...
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Brigham and Women's Hospital
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Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers PHASE2 This phase II trial compares the effect of usual treatment of docetaxel che...
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University of Alabama at Birmingham Cancer Center
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A Real-world Clinical Study of T-DXd for the Treatment of Chinese Patients With HER2 Overexpressing and HER2 Underexpressing Advanced Breast Cancer N/A The study is an open, prospective study to collect data on the efficacy and...
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Multiple Locations
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Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer PHASE2 To evaluate the efficacy and safety of Serplulimab in combination with Tras...
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the First Affiliated Hospital of the Air Force Medical University
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A Study of T-DXd in AI-Assessed HER2-Ultralow Metastatic Breast Cancer NA This is a prospective, multicenter, single-arm study designed to verify the...
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The Second Affiliated Hospital Of Anhui Medical University
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